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Faculty of Graduate Studies
Section 6: Programs in Graduate Studies

6.61  Physiology
Head: Janice Dodd
General Office: 730 William Avenue
Telephone: (204) 789 3694
Fax: (204) 789 3934
Email: physiology@umanitoba.ca
Website: umanitoba.ca/medicine/physiology/

Academic Staff

Program Information
Programs of study leading to the Master of Science and Doctor of Philosophy degrees are offered in several major areas of physiology. A combined M.D./Ph.D. program is available for students who have been admitted to the Faculty of Medicine.

The programs are designed to provide qualified graduates in science and medicine with the background of experience suitable for a career in physiology teaching and research or a research career in clinical medicine.


Fields of Research
The Department of Physiology offers specialized programs of study and research in cardiovascular sciences, molecular endocrinology, gene technology, respiratory and smooth muscle physiology, the cell and molecular biology of cancer, and neurosciences. Updated information on research and training programs are available on the Internet.


Research Facilities
The research laboratories of physiology department members are found in multiple locations. The core laboratories of the department are situated in the Basic Medical Sciences Building of the University of Manitoba Bannatyne Campus (Medical School). Other locations include the Institute of Cell Biology, the National Research Council Institute of Biodiagnostics and the St. Boniface General Hospital Research Centre.


M.Sc. in Physiology

Admission
Admission requirements are those of the Faculty of Graduate Studies found in the Graduate Studies Regulations Section of this Calendar.


Application Deadlines
Canadian/U.S. students should submit their application and supporting documentation to the Department at least 3 months prior to their intended start date. International students should submit their application and supporting documentation to the Department at least 7 months prior to their intended start date.


Program Requirements
A minimum of fifteen (15) credit hours in 700/7000 level courses in Physiology. In most cases, students will be required to complete PHGY 7240 Medical Physiology (6 cr. Hrs.)

Second language reading requirement: none

Expected time to graduate: 2 - 5 years


Ph.D. in Physiology

Admission
Admission requirements are those of the Faculty of Graduate Studies found in the Graduate Studies Regulations Section of this Calendar.


Application Deadlines
Canadian/U.S. students should submit their application and supporting documentation to the Department at least 3 months prior to their intended start date. International students should submit their application and supporting documentation to the Department at least 7 months prior to their intended start date.


Program Requirements
Twelve (12) credit hours beyond the requirements for the M.Sc. degree. Additional courses as deemed appropriate by the Students's Advisory Committee, with the approval of the Physiology Graduate program Committee. Advanced Topics in Physiology ( PHGY 7180) (3) is a required course for Ph.D. students.

Second language requirement: none

Expected time to graduation: 3 - 7 years

Course Descriptions

IMED 7090 Cell Biology Cr.Hrs.6 (Formerly 165.709) Comprehensive introduction to the structure and function of cells. Prerequisite: consent of instructor.

IMED 7180 Molecular Approaches in Medical Research Cr.Hrs.3 (Formerly 165.718) For students who wish to understand advances made in medicine/biology through molecular and developmental approaches. Topics for discussion will be selected from the recent literature in consultation with participating students. The course will consist of lectures and discussions as well as written and oral presentation of papers by the students. Prerequisite: consent of instructor. Offered 2006-2007 and alternate years.

PHGY 7010 Readings in Physiology Cr.Hrs.6 (Formerly 090.701) Tutorial course covering recent contributions in an area of physiology related to a student's research interests.

PHGY 7030 Special Physiology Cr.Hrs.6 (Formerly 090.703) Seminar and reading course on physiology of particular systems.

PHGY 7150 Cardiac Physiology Cr.Hrs.3 (Formerly 090.715) Tutorial and reading course on cardiac physiology; emphasis on the energetics of cardiac contraction and its relationship to ultrastructural and biochemical properties of the heart.

PHGY 7160 Vascular Physiology Cr.Hrs.3 (Formerly 090.716) Lectures and seminars on physiology of blood vessels including hemodynamics, rheology of blood, and the function and structure of smooth muscle.

PHGY 7170 Endocrine and Metabolic Physiology Cr.Hrs.3 (Formerly 090.717) Special topics in endocrine and metabolic physiology emphasizing current concepts.

PHGY 7180 Advanced Topics in Physiology Cr.Hrs.3 (Formerly 090.718) Advances in selected areas of physiology, research proposals related to the students's area of interest, procedures for grant writing and refereeing grant proposals, evaluation of citations and impact factors.

PHGY 7190 Research Topics in Physiology Cr.Hrs.3 (Formerly 090.719) Seminars on research presentations by staff and senior students in physiology.

PHGY 7230 Molecular and Cellular Aspects of Organ Physiology Cr.Hrs.3 (Formerly 090.723) Tutorial course: Function of various organs in the light of current concepts regarding structure and function at the molecular and cellular level.

PHGY 7240 Medical Physiology Cr.Hrs.6 (Formerly 090.724) Lecture, seminar, tutorial, and demonstration course dealing with fundamental biophysical processes, the function of major organ systems, and physiological control mechanisms. Pathophysiological functions and their relation to disease will be discussed where appropriate.

PHGY 7260 Advanced Neurological Sciences Cr.Hrs.3 (Formerly 090.726) Seminar, readings and lecture course covering original research papers leading to the most significant advances in the neurological sciences. Emphasis is placed on student comprehension of major research directions in the broad field of neurological sciences. Prerequisite: PHGY 7280 (or 090.728) or equivalent and consent of instructor.

PHGY 7270 Physiology of Striated Muscle Cr.Hrs.3 (Formerly 090.727) A lecture and seminar course dealing with the physiology and biophysics of skeletal and cardiac muscle.

PHGY 7290 Physiology of the Airways Cr.Hrs.3 (Formerly 090.729) A lecture and seminar course dealing with the physiology of the airways in the intact animal and with the role of smooth muscle in controlling airway function. The fundamental properties of airway smooth muscle in controlling airway function will be emphasized. Prerequisite: PHGY 7240 (or 090.724) or equivalent and consent of instructor.

PHGY 7300 Molecular Endocrinology Cr.Hrs.3 (Formerly 090.730) A lecture and seminar course on advances in molecular and cellular aspects of endocrine and other systems. The course is taught by members of the Gene Technology Group and topics will reflect current research interests. These include the roles of hormones/ growth factors in cancer, growth and development, and reproduction, and the regulation of hormone gene families. This course is designed for individuals with knowledge in the areas of molecular and/or cell biology. Prerequisite: consent of instructor.

PHGY 7310 Principles of Electronics for Life Sciences Cr.Hrs.3 (Formerly 090.731) Lectures on basic principles of electricity and electronics of particular application to electrophysiology.

PHGY 7320 Instrumentation for Electrophysiology Cr.Hrs.3 (Formerly 090.732) Lectures on the application of principles of electricity and electronics to electrophysiology. Prerequisite: PHGY 7310 (or 090.731).

PHGY 7330 Physiology of Smooth Muscle Cr.Hrs.3 (Formerly 090.733) A lecture and seminar course dealing with the biophysics, electrophysiology, pharmacology and biochemistry of the smooth muscle in the major organ systems.

PHGY 7340 Cardiovascular Electrophysiology Cr.Hrs.3 (Formerly 090.734) A comprehensive lecture and seminar course on the electrical properties of cardiac muscle cell membranes, currents and channels as studied by intracellular microelectrodes, voltage clamp and patch clamp techniques.

PHGY 7350 Cardiovascular Pathophysiology Cr.Hrs.3 (Formerly 090.735) A comprehensive lecture course on disease in the cardiovascular system. Topics to be covered include methods of analysis of cardiac viability, heart failure, arrhythmias, heart diseases (congenital, valvular, pericardial, cardiomyopathy), hypertension, stroke, atherosclerosis and myocardial infarction. Prerequisite: PHGY 7240 (or 090.724).

PHGY 7360 Trends in Cardiovascular Sciences Cr.Hrs.3 (Formerly 090.736) A comprehensive seminar-based course dealing with recent advances in cardiovascular research given by local fellows and prominent scientists. Students will be expected to participate in the series and present their own research data seminar. Prerequisite: PHGY 7240 (or 090.724).

PHGY 7370 Cardiovascular Molecular Biology Cr.Hrs.3 (Formerly 090.737) A lecture course dealing with the structure and regulation of genes responsible for normal cardiac muscle and vascular system fluctuations as well as a survey of the genetic contribution to cardio-vascular disease (atherosclerosis, hypertension, heart failure). Prerequisite: PHGY 7240 (or 090.724). Offered alternate years

PHGY 7380 Cardiovascular Cell Biology Cr.Hrs.3 (Formerly 090.738) A comprehensive lecture course on morphology, biochemical composition and function of the cardiac and smooth muscle cell, with particular emphasis on developmental and injury-related issues. Topics include the description of various cardiac cells and their immediate extracellular environment, intercellular communication, cardiac development, control of cell cycle, hyperplasia and hypertrophy, cardiac growth factors, mechanism of injury and cell death, regeneration, heat shock proteins and cardioprotection.

PHGY 7390 Gene Therapy Cr.Hrs.3 (Formerly 090.739) Advanced course detailing new frontiers in the application of gene therapy and technological protocols currently utilized in treating cardiovascular diseases such as cardiomyopathy, hypertension, congenital birth defects and restenosis. Prerequisites: PHGY 7370 (or 090.737), PHGY 7380 (or 090.738) or permission of the course coordinator.

PHGY 7400 Cellular and Molecular Biology of the Vascular System Cr.Hrs.3 (Formerly 090.740) This course provides current concepts in vascular biology at the molecular level as well as the pathogenesis and treatment of vascular diseases for the purpose of graduate studies. Students may also learn up-to-date techniques in research of vascular cell biology and the diagnosis of vascular diseases through laboratory demonstrations. Offered alternate years.

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